Current Research

DIPANJAN CHOWDHURY, PhD

Project Title: “Early diagnosis of ovarian cancer using serum microRNA signatures”

Dr. Chowdhury is an Associate Professor of Medicine at Harvard Medical School and an Associate Professor of Radiation Oncology at the Dana-Farber Cancer Institute.

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Ie-Ming Shih, MD, PhD

Project Title: “Applying DREAMing to detect epigenetic markers in ovarian cancer”

Dr. Shih is the Richard W. TeLinde Distinguished Professor in the Department of Gynecology and Obstetrics at the Johns Hopkins University School of Medicine and a board-certified attending pathologist in the Division of Gynecologic Pathology at the Johns Hopkins Hospital.

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Daniel A. Heller, PhD & Douglas A. Levine, MD

Project Title: “An implantable biomarker nanosensor for early-stage ovarian cancer detection”

Dr. Heller is head of the Cancer Nanomedicine Laboratory at Memorial Sloan Kettering. Dr. Levine is the Director of Gynecologic Oncology, Head of the Gynecology Research Laboratory and a Professor at NYU Langone Perlmutter Cancer Center. Dr. Levine is also Chair of the Tina’s Wish Scientific Advisory Board. Dr. Levine and Dr. Heller are Co-Principal Investigators on this project.

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Douglas A. Levine, MD &   Kara Long Roche, MD

Project Title: “Circulating and shed biomarkers for early detection of ovarian cancer””

Dr. Levine is the Director of Gynecologic Oncology, Head of the Gynecology Research Laboratory and a Professor at NYU Langone Perlmutter Cancer Center. Dr. Levine is Chair of the Tina’s Wish Scientific Advisory Board. Dr. Long Roche is a gynecologic oncologist at Memorial Sloan Kettering Cancer Center. Dr. Levine and Dr. Roche are Co-Principal Investigators on this project.

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Ronny Drapkin, MD, PhD & Jarrod Marto, PhD

Project Title: “Biomarker discovery in tissue proximal fluids”

Dr. Drapkin is an Associate Professor of Obstetrics, Gynecology and Pathology at the University of Pennsylvania and the Director of the Ovarian Cancer Research Center at Penn Medicine. Dr. Marto is an Associate Professor of Biological Chemistry and Molecular Pharmacology at Harvard Medical School and Director of the Blais Proteomics Center and Principal Investigator for the Department of Cancer Biology at Dana-Farber Cancer Institute. Dr. Drapkin and Dr. Marto are Co-Principal Investigators on this project.

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Ronald Buckanovich, MD & Kathleen Cho, MD

Project Title: “Developing a novel, non-toxic ovarian cancer prevention therapy”

Dr. Buckanovich is an Associate Professor of Internal Medicine and Obstetrics and Gynecology at the University of Michigan. Dr. Cho is a Professor of Pathology at the University of Michigan. Dr. Buckanovich and Dr. Cho are Co-Principal Investigators on this project.

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Charles Landen, MD, MS

Project Title: “Detection of early-stage ovarian cancer through vaginal sampling”

Chip Landen, MD is a gynecologic oncologist and an Associate Professor in the Gynecologic Oncology Division at the University of Virginia and the Associate Leader of the Women's Oncology Program at the UVA Cancer Center.

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Abhijit Patel, MD, PhD & Alessandro Santin, MD

Project Title: “Early detection of ovarian cancer via analysis of genomic alterations in DNA and RNA from multiple sources in blood”

Dr. Patel is an Assistant Professor of Therapeutic Radiology at Yale Cancer Center. Dr. Santin is a Professor of Obstetrics, Gynecology, and Reproductive Sciences at Yale Cancer Center. Dr. Patel and Dr. Santin are Co-Principal Investigators on this project.

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Rising Star Grant, Kevin Elias, MD

Project Title: “A murine model for early ovarian cancer detection using circulating microRNA”

Dr. Elias is a physician-scientist in Gynecologic Oncology with appointments at Brigham and Women’s Hospital, the Dana-Farber Cancer Institute, and Harvard Medical School.

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Rising Star Grant, Lan Gardner Coffman, MD

Project Title: “Targeting the formation of carcinoma-associated mesenchymal stem cells to prevent the establishment of the ovarian cancer microenvironment”

Dr. Coffman is a clinical lecturer in the division of Hematology/Oncology. She is board certified in internal medicine and medical oncology and is pursuing a career as a physician scientist with a clinical focus on ovarian cancer and research focus on the tumor microenvironment.

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Consortium Grant, Ronny Drapkin, MD, PhD, Daniel Heller, PhD, Ie-Ming Shih, MD, PhD, Rugang Zhang, PhD

Project Title: “Integration of Advanced Genomic and Bioengineering Approaches for early Detection and Prevention of Ovarian Cancer”

Tina's Wish is honored to present its second Consortium Grant to this cutting edge team of researchers who will collaborate together for the next three years.

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#1

deadliest gynecologic
cancer

80%

of women are diagnosed
at an advanced stage

27%

of women have a 5-year
survival rate after an
advanced stage diagnosis