Project Title: “Epigenetic cell-free DNA biomarkers for ovarian cancer detection”
Dr. He is a chemical biologist and the John T. Wilson Distinguished Service Professor at the University of Chicago. Dr. Lengyel is an Arthur L. and Lee G. Herbst Professor of Obstetrics and Gynecology and Chair of the Department of Obstetrics and Gynecology at University of Chicago.
Project Title: “Non-invasive liquid biopsy approach for early detection of ovarian cancer using cell free DNA fragmentation patterns”
Dr. Konecny is a Professor of Oncology and Obstetrics and Gynecology, and the Director of Medical Gynecologic Oncology at UCLA. Dr. Velculescu is Co-Director of Cancer Genetics and Epigenetics, and a Professor of Oncology and Pathology at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.
Project Title: “Bioanalytical platform for identification and validation of ovarian cancer biomarkers in tissues and proximal fluids”
Dr. Drapkin is an Associate Professor of Obstetrics, Gynecology and Pathology at the University of Pennsylvania and the Director of the Ovarian Cancer Research Center at Penn Medicine. Dr. Marto is an Associate Professor of Biological Chemistry and Molecular Pharmacology at Harvard Medical School and Director of the Blais Proteomics Center and Principal Investigator for the Department of Cancer Biology at Dana-Farber Cancer Institute. Dr. Drapkin and Dr. Marto are Co-Principal Investigators on this project.
Project Title: “Monitoring Intrauterine Biomarkers to Detect Pre-Invasive Disease”
Dr. Heller is head of the Cancer Nanomedicine Laboratory at Memorial Sloan Kettering. Dr. Long Roche is a gynecologic oncologist at the Memorial Sloan Kettering Cancer Center. Dr. Long Roche and Dr. Heller are Co-Principal Investigators on this project.
Many thanks to Douglas A. Levine, MD, of NYU Perlmutter Cancer Center, for his contributions as Co-PI during the first phase of this project.
Project Title: “Stromal biomarkers for enhanced detection of early-stage ovarian cancer”
Dr. Coffman is an Assistant Professor of hematology/oncology in the division of gynecologic oncology at the University of Pittsburgh and a physician scientist at Magee-Women’s Research Institute & Foundation. Dr. Pisanic is a Senior Research Scientist at the Johns Hopkins Institute for NanoBioTechnology.
Project Title: “PapDREAMS – a combined genetic and epigenetic multi-analyte assay for early detection of ovarian cancer in tissue proximal fluids”
Dr. Shih is a Richard W. TeLinde Distinguished Professor in the Department of Gynecology and Obstetrics at the Johns Hopkins University School of Medicine and a board-certified attending pathologist in the Division of Gynecologic Pathology at the Johns Hopkins Hospital. Dr. Pisanic is a Senior Research Scientist at The Johns Hopkins Institute for NanoBioTechnology. Dr. Wang is a professor in the Departments of Mechanical Engineering and Biomedical Engineering at the Johns Hopkins University and a Core Researcher at the Johns Hopkins Institute for NanoBioTechnology.
